Mark, I don't really see a cubic inch limit to valve sizing but more of a bore diameter limit moreso? 4.3?? bore is much harder to get a 2.35 valve into, and 99 times out of a 100 you need to move around the dowels to accomplish this.
So as long as you're 4.4++ bore, always try and go bigger valve. Again Foxwell wants to put out thought on formulas for HIS thoughts, but even though they were a bit smaller, back 10+ years ago, BES 525 used NMCA legal at the time 2.350 valve BMF 350's (385 and 405's were not "LEGAL"). These through an UNCUT or WELDED cast single made 1180Hp and turned 94/9500 rpm. I had MANY a long talk with Tony about these as my 499 short was at least as well thought out as these, and my Pontiac "427" worked abit more. So like many have stated, back then the heads/intake was worth about 100 more, which turned out pretty close. BUT I did have 2.400 valve.
Jeff C onn here used to do some 565's with 2.35 and usually made well north of 2.1Hp per inch. PM guys like Abbottracingheads and Slick Rick on here. Those 2 played in the TPS days of conventional heads and would know pretty well what is REALLY required at that cubic inch size.
FYI I believe the highest Hp conventional head, NON SR20 with a single is Alex Hayes 588 with BMF 330's and cast SNIPER. Made 1330Hp with Slick Rick induction.
Now your $3500 budget BARE!!!! There are a ton of heads out there and most will work very good by the time you fill them and tailor them YOUR combo. I don't think there is a "best" but HH have been well received and so has the Profilier Snipers. BUT I'm sur you would by much better off with a good USED set from guys moving up to the SR20 stuff.