I think mainly Dan meant, how much power are you wanting to make, will it be drag race only, road race, street only, nitrous/boost, etc...
There are the cheaper $1000 kits that will hold up about as well as a stock 351 late model block. Say around 600-700 fwhp at most. Then there are the forged kits out there that can handle 1000 horsepower plus with supporting parts.
Is this going in a 75 and newer block, or in a 69-74 block? The older blocks are stronger and would make it beneficial to go with all 4340 stuff so you can handle more power in the future.
I have all Eagle 4340 crank/h-beam rods with Ross forged flat tops on my combo. No problems so far with around 650 n/a and 750-800 (maybe) on nitrous. I plan to make some more n/a and hit it with 300 this year.