See I tend to think spool will not be effected a whole heck of a lot. But, E85 likes higher compression and your off boost will be better. Power will also be better. But I really don't think spool will be a lot different.
U have a better transient response with higher commoression. Normally with higher compression Turbo car will make more power per psi but the tune has to be spot on. Also the huger compression u go the more your limited on pump gas.